Observational Study of Seizure Management in Critically Ill Children

This study is looking at how seizures are managed in critically ill children at Children's Hospital of Philadelphia. Researchers are observing children who are already getting continuous EEG monitoring (a test that measures brain activity) as part of their regular care. The goal is to understand what puts children at risk for seizures and to see how well current seizure management strategies work. This study is not testing a new medicine; it's observing how doctors currently use clinically indicated EEG monitoring and seizure management. You might be able to join if you are a child between 1 month and 18 years old, are in the Pediatric ICU at CHOP, and are already getting continuous EEG monitoring. The study will look at how often seizures happen over 3 days.

Study design
This is an observational study involving about 2500 participants. It is not testing a specific treatment, but rather observing current medical practices.
What's involved
Children in this study will undergo clinically indicated continuous EEG monitoring and some will receive clinically indicated electrographic seizure management, as part of their regular care.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, electrographic seizure occurrence, is measured at 3 days.

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NCT03419260

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

Recruiting
Not specifiedAges 1–18Observational
Children's Hospital of Philadelphia
~2,500 participants
Updated 2026-06-29 on ClinicalTrials.gov
What's tested:Clinically indicated EEG monitoring.

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Electrographic Seizure Occurrence
Measured over 3 days
Seizures
1 sites across 1 states
Pennsylvania1
  • Nicholas S Abend, MD · PRINCIPAL_INVESTIGATOR · Children's Hospital of Philadelphia

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  • Electrographic Seizure Occurrence3 days

    Percentage of subjects who experience electrographic seizures.