EXPAREL for Post-Tonsillectomy Pain
This study is looking at ways to manage pain after a tonsillectomy (surgery to remove your tonsils). It compares two approaches: the standard pain medication, bupivacaine HCl 0.25% with epinephrine, and a combination of this standard medication with Exparel (bupivacaine liposome suspension 1.3%). Researchers want to see if adding Exparel helps reduce pain, especially in the first three days after surgery, and if it lowers the need for other pain medications. You may be able to join if you are an adult (18 years or older) scheduled for a tonsillectomy. The study aims to enroll 38 participants. The success of the study will be measured by changes in your pain rating from right after surgery up to 10 days later. The current status of this study is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 38 adult participants.
- What's involved
- After your tonsils are removed and before you wake up from anesthesia, the study doctor will inject medication into the surgical area. Your pain levels will be measured on days 1, 2, 3, 5, and 10 after surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your pain will be monitored for 10 days after your tonsillectomy.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
EXPAREL Post-tonsillectomy Clinical Trial
At a glance
Conditions
Where it's being run
2 sites across 1 statesWho to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change in pain rating between post anesthesia care unit (PACU) baseline and designated post-operative daysPost-tonsillectomy Days 1, 2, 3, 5, and 10
Patient reported average and maximum pain rating over a 24-hour period using the St. Joseph Mercy Ann Arbor (SJMAA) standard visual analog 11 point pain rating scale. The minimum value of 0 indicates no pain and the maximum value of 10 indicates the worst possible pain. A higher value represent greater pain and a worse outcome. The baseline pain rating is the maximum rating from PACU on the day of surgery. Day-1 begins at 12:00 AM (after midnight) day of surgery and extends through 11:59 PM. Each following designated day will begin at 12:00 AM and extend through 11:59 PM.