Back to search results

Biospecimen Procurement for Head and Neck Disorders

Researchers are collecting tissue samples to learn more about head and neck disorders, such as hearing problems, oral diseases, and cancers. This study aims to create a collection of diseased and normal tissue samples for future research. You might be able to join if you are 3 years or older and have a head and neck condition that requires tissue removal for medical care or other research. The goal is to build a resource that helps scientists understand these conditions better and potentially find new treatments. This is an observational study, meaning no new treatments are being tested, and its current status is unclear.

Study design
This is an observational study that plans to enroll up to 1000 participants. It involves collecting tissue samples that are already being removed for medical reasons or from previous research.
What's involved
You would give permission for leftover tissue samples from your medical care or other research to be used. You will also complete a questionnaire, medical history, and physical exam.
Compensation
Not stated in the trial record.
Follow-up
The primary goal of creating the tissue collection is measured until June 3, 2026. It is not specified how long individual participants are followed.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03429036

Biospecimen Procurement for Head and Neck Disorders

Recruiting
Not specifiedAges 3+Observational
National Cancer Institute (NCI)
~1,000 participants
Updated 2026-08-28 on ClinicalTrials.gov

At a glance

Recruiting sites
9 of 9 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To created a biorepository of diseased and normal tissue specimens for research purposes
Measured over 06/03/2026

Conditions

Hearing Disorder
Oral Mucosal Disease
Pharyngeal Neoplasm
Head and Neck Neoplasms
Laryngeal Disease

Explore related trials

Disorder of oral mucous membraneHearing DisorderLaryngeal DisorderPharyngeal Neoplasm

Where it's being run

9 sites across 2 states
Maryland6
District of Columbia3

Study leadership

  • Clint T Allen, M.D. · PRINCIPAL_INVESTIGATOR · National Cancer Institute (NCI)

Who to contact

Melissa L Wheatley
[email protected]
(240) 858-3391
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Age 3 and older.
Able to provide their own consent, or for minors, a parent or guardian is able to consent on their behalf.
Diagnosis of a condition of the head and neck for which removal of biological specimens was indicated for clinical care or for research purposes under a separate Review Board (IRB) approved protocol.
Ability of subject (or Legally Authorized Representative (LAR)) to understand and the willingness to sign a written informed consent document.

Exclusion

Part 1:
Are unwilling to share waste specimens for research purposes
have active symptomatic major organ disorders that would increase the risk of biopsy for research, including but not limited to bleeding disorders, ischemic heart disease, a recent myocardial infarction, active congestive heart failure or severe pulmonary dysfunction
have specific medical condition, such as a bleeding tendency where additional biopsies or phlebotomy procedures may increase the participants' risk in participating. This will be determined at the discretion of the principal investigator
Individuals under the age of 18 are excluded from oral mucosal biopsies and skin biopsies

What this trial measures

  • To created a biorepository of diseased and normal tissue specimens for research purposes06/03/2026

    The primary endpoint of this study is the creation of a head and neck biorepository from both surgical waste material and prospectively collected blood, saliva, oral swabs, oral mucosa biopsy and skin biopsy specimens.