This study is looking at how familial pulmonary fibrosis (FPF) develops in families where multiple members have a lung condition called idiopathic interstitial pneumonia (IIP). FPF is the family form of idiopathic pulmonary fibrosis (IPF), a serious lung disease. Researchers want to understand why some family members get the disease and others don't, and what factors might contribute to it. You could be eligible if you are between 40 and 75 years old and are a blood relative (like a sibling or adult child) of someone diagnosed with IIP, but you don't have IIP or IPF yourself. The study will follow participants until at least January 2030 to see if changes in blood, CT scans, or lung function can predict who will develop pulmonary fibrosis.

Study design

This is an observational study aiming to enroll 750 participants. It is not testing a specific treatment, but rather observing how a disease develops over time.

What's involved

You would first complete a questionnaire and consent form. If eligible, you would undergo further evaluations including HRCT scans (detailed lung X-rays), pulmonary function tests (PFTs), and blood draws. These visits may also include an additional questionnaire, a urine sample, and the use of wearable devices. You may be asked to return for repeat tests approximately every 3 years.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed until at least January 2030 to track the clinical diagnosis of interstitial lung disease.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.