Resilience in Adolescent Development Study

This study, called RAD, is looking for 1500 young people aged 10 to 24 to understand what helps them be resilient, especially if they are at risk for mood and anxiety disorders like depression. It's an observational study, meaning researchers will watch and collect information over 10 years without giving any treatments or interventions. They want to find out what social, lifestyle, psychological, and biological factors contribute to resilience. You can join if you are between 10 and 24 years old, can speak and read English, and your parent or guardian can speak English or Spanish. The main goal is to see how depression severity changes over 10 years and identify protective factors that reduce the risk of these conditions.

Study design
This is an observational study planning to enroll 1500 participants. It is a natural history, longitudinal, prospective assessment study.
What's involved
You would participate in assessments over 10 years, which include questionnaires about symptoms, social factors, and quality of life. Other assessments may include measures of brain function and biochemical markers.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 10 years to assess depression severity and other outcomes.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03458936

Resilience in Adolescent Development

Active, Not Recruiting
Not specifiedAges 10–24Observational
University of Texas Southwestern Medical Center
~1,500 participants
Updated 2026-06-01 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Depression Severity
Measured over 10 Years
Risk Assessment
Resilience, Psychological
Depression
Mood Disorders
Anxiety Disorders
Mental Health
1 sites across 1 states
Texas1
  • Madhukar H. Trivedi, MD · PRINCIPAL_INVESTIGATOR · UT Southwestern

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Depression Severity10 Years

    Longitudinal changes in depression presence and severity of participants without a mood disorder on Patient Health Questionnaire (PHQ-9). Interpretation of Total Scores: 0-4: Minimal depression or no depression 5-9: Mild depression 10-14: Moderate depression 15-19: Moderately severe depression 20-27: Severe depression