Stroke Motor Rehabilitation and Recovery Study (SMaHRT)

This study, called SMaHRT, aims to understand how people recover arm movement after a stroke (when blood flow to the brain is interrupted, either by a clot or bleeding). Researchers will follow participants over time to learn about the natural recovery process. You might be able to join if you are between 18 and 90 years old, have some arm weakness after an ischemic (clot-related) or hemorrhagic (bleeding-related) stroke, and can follow simple commands in English. The main way success is measured in this study is by tracking your arm movement using a test called the Fugl-Meyer Arm Motor Assessment over approximately one year. The current status of this study is unclear.

Study design
This is an observational study planning to enroll 300 participants. It is designed to watch and record how people recover naturally after a stroke.
What's involved
You would have research visits during your acute hospitalization and then at approximately 6 weeks, 3 months, 6 months, one year, two years, and three years after your stroke. These visits may include collecting demographics, clinical measurements, neuroimages, video, and brain activity data.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to three years after their stroke date.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03485040

Stroke Motor Rehabilitation and Recovery Study

Recruiting
Not specifiedAges 18–90Observational
Massachusetts General Hospital
~300 participants
Updated 2025-05-15 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Fugl-Meyer Arm Motor Assessment
Measured over Time 1: During acute hospitalization; Time 2: approx. 6 weeks after stroke date; Time 3: approx. 90 days after stroke date; Time 4: approx. 180 days after stroke date; Time 5: approx. 1 year after stroke date Time 6: N/A; Time 7: N/A
Stroke, Ischemic

NCT03485040

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Massachusetts General Hospital

    Boston, Massachusettsno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • David J Lin, MD · PRINCIPAL_INVESTIGATOR · Neurologist

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Eligibility criteria

Inclusion

Age 18 - 90
Upper extremity motor weakness after ischemic and/or hemorrhagic stroke as defined by a score of \>=1 on NIH Stroke Scale Arm Motor Drift Questions 5A or 5B
Ability to follow simple commands in English
Score of zero or 1 on the NIH Stroke Scale Level of Consciousness Questions 1a and 1b and a score of zero on the NIH Stroke Scale Level of Consciousness Question 1c.
Stable medical status as determined by primary care team
Inpatient on the MGH stroke neurology service

Exclusion

Prior history of developmental, neurologic, or major psychiatric disorder resulting in functional disability
Prior history of visual or auditory disorders limiting ability to participate in testing
Evidence of an uncontrolled seizure disorder
Patients for whom EEG leads are contraindicated
  • Fugl-Meyer Arm Motor AssessmentTime 1: During acute hospitalization; Time 2: approx. 6 weeks after stroke date; Time 3: approx. 90 days after stroke date; Time 4: approx. 180 days after stroke date; Time 5: approx. 1 year after stroke date Time 6: N/A; Time 7: N/A

    This test provides information about level of upper extremity motor impairment after stroke. The test includes a series of different movements that allow for the assessment of functional movement capacity and quality. The scale is used to track change in upper extremity motor impairment over the course of one year post stroke.