CPAP for Sleep Apnea in Pregnancy

This study is looking at whether treating obstructive sleep apnea (OSA) during pregnancy with Continuous Positive Airway Pressure (CPAP) can lower the risk of developing high blood pressure conditions like preeclampsia. Researchers will compare CPAP treatment, which involves a device worn during sleep, to receiving only sleep advice. They want to see if CPAP reduces the number of women who develop high blood pressure disorders of pregnancy. You may be able to join if you are a woman, 18 years or older, and are between 14 and 21 weeks pregnant with one baby. The study aims to enroll 1,500 women. The current status of the study is unclear.

Study design
This is an interventional study that plans to enroll 1,500 women. Participants will be randomly assigned to receive either CPAP treatment or sleep advice.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The main outcome will be measured up to 14 days after you give birth.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03487185

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

Active, Not Recruiting
NAAges 18+InterventionalPrevention
The George Washington University Biostatistics Center
~1,500 participants
Updated 2026-08-05 on ClinicalTrials.gov
What's tested:Continuous Positive Airway PressureSleep Advice Control

At a glance

Recruiting sites
0 of 14 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Diagnosis of Hypertensive Disorders of Pregnancy
Measured over Up to 14 days postpartum
Obstructive Sleep Apnea of Adult
Preeclampsia
Obstetrical Complications
14 sites across 10 states
Texas3
Ohio2
Pennsylvania2
Alabama1
California1
Illinois1
New York1
North Carolina1
  • Rebecca Clifton, PhD · PRINCIPAL_INVESTIGATOR · The George Washington University Biostatistics Center
  • Monica Longo, MD · STUDY_DIRECTOR · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  • Francesca Facco, MD · STUDY_CHAIR · Magee Women's Hospital of UPMC

This trial hasn't published a contact. View it on ClinicalTrials.gov

  • Diagnosis of Hypertensive Disorders of PregnancyUp to 14 days postpartum

    Subjects are considered to have the primary outcome if they meet the criteria for eclampsia, HELLP, atypical HELLP, preeclampsia, superimposed preeclampsia or antepartum gestational hypertension.