This study is looking at people who are already part of the UAB Alzheimer's Disease Center (ADC) study. Researchers want to understand more about Alzheimer's disease by using a special brain scan called [C-11]PiB-PET/MRI. This scan helps measure a protein called beta-amyloid, which is linked to Alzheimer's. The study aims to see how beta-amyloid levels relate to a person's race, risk factors for blood vessel problems, and thinking abilities. To join, you must already be enrolled in the UAB-ADC study and be at least 50 years old. The main goal is to measure beta-amyloid in the brain over 5 years.

Study design

This is an interventional study planning to enroll 160 participants. It involves a specific brain imaging procedure.

What's involved

All participants will undergo a brain imaging scan using [C-11]PiB-PET/MRI. Women of childbearing potential will need a negative pregnancy test before the scan.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint, measurement of pathological beta-amyloid in the brain, will be taken at 5 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.