Personalized Treatment in Thyroid Disorders with CoTI
This study is testing a device called the Cervical Collar Therapy Indicator (CoTI) for people with thyroid cancer or Graves' disease. The CoTI is a collar worn around the neck that continuously measures radiation exposure during radioiodine treatment. Researchers believe this device will provide more accurate estimates of radiation exposure to thyroid tissue compared to current methods. The goal is to help doctors give the best possible dose of radioiodine to each patient, potentially reducing side effects and improving treatment success. The study will evaluate how much the radioiodine levels vary in patients over 6-9 months. You may be able to join if you are between 21 and 65 years old, understand English, and have either Graves' disease or certain types of thyroid cancer requiring radioiodine treatment. The current status of the study is unclear.
- Study design
- This is an interventional study with a planned enrollment of 10 participants. It is not specified if it is randomized or blinded.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study will evaluate radioiodine kinetics for patients over 6-9 months.
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Personalized Treatment in Thyroid Disorders
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Prasanna Santhanam, MBBS, MD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Evaluation of the Variability in radioiodine kinetics for patients with thyroid cancer and graves disease6-9 months
Radioactive iodine uptake at different time points will be taken over a 24 hour period (7 days for thyroid cancer) and then the Area Under the Curve (AUC) will be Plotted.The AUC would then be correlated with the 24 hour uptake in Graves and day 7 uptake for thyroid cancer.We will use non-parametric tests to measure the correlation