NCT03541785
Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI
Enrolling by Invitation
Not specifiedAges 3–25ObservationalChildren's Hospital Medical Center, CincinnatiInvestigator-initiated
~420 participants
Updated 2026-03-23 on ClinicalTrials.gov
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Clinical Decision Support Success (CDS)
Measured over 48 hours of PICU admission
Conditions
Where it's being run
1 sites across 1 statesOhio1
Study leadership
- Stuart Goldstein, MD · PRINCIPAL_INVESTIGATOR · Children's Hospital Medical Center, Cincinnati
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Admitted to the Pediatric Intensive Care Unit (PICU)
Renal Angina Index (RAI) greater than or equal to 8
Urine NGAL greater than or equal to 150 ng/mL
Indwelling urinary catheter
Exclusion
Evidence of volume depletion
Baseline Chronic Kidney Disease (CKD) Stage IV or V (estimated GFR \<60 mL/min/1.73m2)
History of kidney transplantation
Active DNR order or clinical team is not committed to escalating medical care
Known history of allergic reaction to furosemide (only for FST)
What this trial measures
- Clinical Decision Support Success (CDS)48 hours of PICU admission
Time to complete risk stratification (RAI), biomarker testing (NGAL), and functional kidney assessment (FST) is less than 48 hours