This study is looking at a new way to image the heart using a special tracer called 11C-Martinostat and a PET-MRI scanner. Researchers want to see how this tracer binds to something called histone deacetylase (HDAC) in the heart. HDACs are enzymes that play a role in heart conditions like heart failure and thickening of the heart muscle (left ventricular hypertrophy). The study aims to understand how HDACs work in healthy people, and in those with diabetes or a heart condition called aortic valve stenosis. This could help doctors better understand these conditions and develop new treatments. The study is currently recruiting participants aged 18 to 85 years, including healthy volunteers and patients with diabetes.

Study design

This interventional study plans to enroll 96 participants, including healthy volunteers and patients with diabetes. It is not specified if the study is randomized or blinded.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

The primary endpoint, 11C-Martinostat binding, is measured at 10-60 minutes post-injection. It is not specified if there is follow-up beyond this timeframe.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.