Timed Aspirin Chronobiome Study for Blood Pressure

This study is looking at whether taking a low dose of aspirin (81 mg) in the evening can help prevent the blood pressure increase that sometimes happens when people take celecoxib (200 mg capsule), a common pain medication. Researchers want to see if this timed aspirin administration can be a simple way to reduce this side effect. You might be able to join if you are a healthy adult, 18 years or older. The study will measure your blood pressure after 24-48 hours to see if the aspirin helps. The current recruitment status is unclear, but the study plans to enroll 60 participants.

Study design
This is an interventional study with 60 planned participants. It is not specified if it's randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Blood pressure will be measured at 24-48 hours after the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03590821

Timed Aspirin Chronobiome Study

Not Yet Recruiting
EARLY_PHASE1Ages 18+InterventionalPrevention
University of Pennsylvania
~60 participants
Updated 2026-05-29 on ClinicalTrials.gov
What's tested:Aspirin 81 mgCelecoxib 200mg capsule

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Blood pressure [mmHg]
Measured over 24-48 hours
Healthy
1 sites across 1 states
Pennsylvania1
  • Carsten Skarke, MD · PRINCIPAL_INVESTIGATOR · University of Pennsylvania

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  • Blood pressure [mmHg]24-48 hours

    Ambulatory blood pressure measurements