Radiotracer-Based Perfusion Imaging for Peripheral Artery Disease

This study is looking at how well special imaging tests, called SPECT/CT and PET/CT perfusion imaging, can help doctors understand and predict outcomes for people with Peripheral Artery Disease (PAD). PAD is a condition where narrowed arteries reduce blood flow to your limbs. You might be able to join if you are at least 18 years old and have PAD that requires a revascularization procedure (a procedure to restore blood flow). The study aims to see if these imaging tests can accurately measure blood flow in your legs and show how well treatments are working. The study plans to enroll 192 participants, but its current status is unclear.

Study design
This interventional study plans to enroll 192 participants, including those with PAD and healthy volunteers. It will compare imaging results before and after revascularization procedures.
What's involved
If you join, you will have SPECT/CT or PET/CT perfusion imaging before and 1-14 days after your revascularization procedure. This involves an intravenous (IV) injection of a small amount of a radiotracer for each imaging session.
Compensation
Not stated in the trial record.
Follow-up
Clinical outcomes will be evaluated for up to 12 months after the imaging study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03622359

Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease

Recruiting
NAAges 18+InterventionalDiagnostic
Nationwide Children's Hospital
~192 participants
Updated 2025-04-01 on ClinicalTrials.gov
What's tested:SPECT/CT perfusion imagingPET/CT perfusion imaging

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Lower extremity perfusion
Measured over 1-2 weeks
Peripheral Artery Disease
Diabetes Mellitus
Chronic Limb-Threatening Ischemia
1 sites across 1 states
Ohio1
  • Mitchel R Stacy, Ph.D. · PRINCIPAL_INVESTIGATOR · Nationwide Children's Hospital

Opens a ready-to-send draft in your own email app — review before sending.

  • Lower extremity perfusion1-2 weeks

    The percent or absolute change in perfusion from baseline to post-revascularization will be evaluated.