Alzheimer Prevention Trials (APT) Webstudy

This observational study, called the Alzheimer Prevention Trials (APT) Webstudy, aims to find people who might be at a higher risk for developing Alzheimer's disease. There are no specific interventions (like drugs) being tested. The goal is to enroll people into other Alzheimer's prevention research studies over five years. You can join if you are between 50 and 85 years old, do not have dementia, and are willing to do cognitive tests online and possibly have biomarker assessments (tests that look for signs of disease in your body). The study is looking to enroll 200,000 people. The current recruitment status is unclear.

Study design
This is an observational study with a planned enrollment of 200,000 participants. It is not specified if it is randomized or blinded.
What's involved
You will register online, sign a consent form, provide basic information, and complete web-based cognitive testing. You will return every three months to complete the cognitive testing again.
Compensation
Not stated in the trial record.
Follow-up
The primary goal is enrollment into other research studies, measured at 5 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03638583

Alzheimer Prevention Trials (APT) Webstudy

Recruiting
Not specifiedAges 50–85Observational
University of Southern California
~200,000 participants
Updated 2025-07-16 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Enrollment into Alzheimer's prevention research studies
Measured over 5 years
Alzheimer Disease
Dementia
1 sites across 1 states
California1
  • Paul Aisen, MD · PRINCIPAL_INVESTIGATOR · USC ATRI
  • Reisa Sperling, MD · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital
  • Jeffrey Cummings, MD · PRINCIPAL_INVESTIGATOR · The Cleveland Clinic

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

male or female at least 50 years of age
no evidence of dementia
willing to participate in remote longitudinal cognitive testing and possible referral for biomarker assessment based on risk

Exclusion

N/A. Anyone can register for the APT Webstudy, however, only individuals identified using the risk algorithm will be referred for in-person biomarker assessments.
  • Enrollment into Alzheimer's prevention research studies5 years