Observational MRI Study in Bronchopulmonary Dysplasia (BPD)
This study is looking at how the lungs develop in babies, especially those with Bronchopulmonary Dysplasia (BPD), a breathing problem common in premature infants. Researchers will use an MRI device (a machine that uses magnets and radio waves to create detailed pictures of organs and structures inside the body) to take images of the lungs. They will also use Polysomnography (a sleep study that records brain waves, oxygen levels, heart rate, and breathing during sleep) to understand breathing issues. The main goal is to see how lung anatomy looks on MRI. This study is for NICU patients up to 4 months old, but excludes those with certain other health conditions. The study is currently unclear on its recruitment status and plans to enroll 160 participants.
- Study design
- This is an observational study involving 160 participants. It is not a randomized trial and does not specify a phase.
- What's involved
- Participants will have up to three MRI visits, with the first after initial evaluation, the second about one month later, and the third before discharge. Some participants may also have a brief inpatient polysomnogram in the NICU.
- Compensation
- Not stated in the trial record.
- Follow-up
- Anatomic phenotypes using MRI are measured at baseline, but no further follow-up duration is specified.
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MRI in BPD Subjects
At a glance
Conditions
NCT03657693
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Megan Schmitt
Cincinnati, Ohiostudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Jason Woods, PhD · PRINCIPAL_INVESTIGATOR · Children's Hospital Medical Center, Cincinnati
Who to contact
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Inclusion
Exclusion
What this trial measures
- Anatomic phenotypes using MRIbaseline
Investigate parenchymal and vascular structures, regional cardiopulmonary function, and dynamic airway collapse in BPD infants during quiet unsedated breathing.