Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

This study is looking at a new approach for Alzheimer's disease and related memory problems. It tests a combination of 40Hz light therapy and cognitive therapy, delivered through an iPad application called ALZLIFE. The idea is that 40Hz light may help increase "gamma" brainwaves, which are important for brain function and are often reduced in Alzheimer's. This could potentially help clear harmful proteins in the brain. You might be able to join if you are 50 years or older and have Alzheimer's disease or cognitive impairment (problems with thinking and memory). You cannot have a history of seizures or significant eye disease like macular degeneration. The study will measure success by looking at your cognitive test results over about one year. The current status of this study is unclear.

Study design
This is an observational study planning to include 2000 participants. It is not specified if participants are randomly assigned to groups or if the study is blinded.
What's involved
The primary endpoint is an in-app cognitive test measured through study completion, which is an average of one year.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for an average of one year, which is the duration of the study completion.

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NCT03657745

Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

Recruiting
Not specifiedAges 50+Observational
Alzheimer's Light LLC
~2,000 participants
Updated 2024-08-01 on ClinicalTrials.gov
What's tested:Combination of 40Hz light and cognitive therapy (ALZLIFE)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
In-app cognitive test
Measured over through study completion, an average of 1 year
Alzheimer Disease
Mild Cognitive Impairment
Dementia
Cognition Disorders in Old Age
Cognitive Decline
Cognitive Deterioration
1 sites across 1 states
Florida1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Alzheimer's disease
Cognitive Impairment

Exclusion

any previously noted epileptic seizures, including febrile seizures.
any significant disease of the eye, such as macular degeneration. Since the 40Hz light therapy is delivered via eye stimulation, healthy eyes are required.
  • In-app cognitive testthrough study completion, an average of 1 year

    The cognitive therapy delivered by ALZLIFE consist of cognitive games: Sudoku, Tic-Tac-Toe, Analog clock comparison, etc. The changes in performance score in these cognitive games are used to calculate the participant's Cognitive Index. Cognitive Index maximum score = 100. The lower score indicates worse performance.