Caffeine Consumption in Glaucoma Patients and Healthy Subjects
This study is looking at how caffeine affects blood flow in the back of the eye for people with glaucoma and healthy individuals. Participants will receive one 200 mg caffeine tablet. Researchers will measure blood flow changes in the back of your eye before and after taking caffeine using a special imaging tool called optical coherence tomography angiography (OCTA). This helps them see how caffeine might decrease blood flow. The study aims to enroll 80 people between 18 and 90 years old, including those with primary open-angle glaucoma and healthy individuals without eye disease. The current status of the study is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific intervention (a caffeine tablet). It plans to enroll 80 participants.
- What's involved
- You would complete baseline study tasks, then ingest a 200 mg caffeine tablet. Blood flow in the back of your eye will be measured at baseline, Hour 1, and Hour 2.
- Compensation
- Not stated in the trial record.
- Follow-up
- Blood flow changes are measured at Baseline, Hour 1, and Hour 2 after caffeine intake.
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Caffeine Consumption in Glaucoma Patients and Healthy Subjects
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- M. Reza Razeghinejad, MD · PRINCIPAL_INVESTIGATOR · Wills Eye Hospital
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Blood flow change in back of eye before and after caffeineBaseline, Hour 1, Hour 2
Optical Coherence Tomography Angiography (OCTA) will be obtained using the Avanti AngioVue High Definition (HD) OCTA by Optovue. Images will include standard 4.5mm HD disc scan, 6mm HD retina scan, regular optic nerve head (ONH) structural scan, 3D-disc baseline scan and a regular ganglion cell complex analysis (GCCA) structural scan. This will measure blood flow changes in the back of the eye by imaging vessel density in percentage before then 1 and 2 hours after caffeine.