This study aims to understand how much lung inflammation occurs in different groups: e-cigarette users (vapers), cigarette smokers, and non-smokers. Researchers will use a special imaging drug called [18F]NOS (an investigational radiotracer) with a PET/CT scan (Positron Emission Tomography/Computed Tomography, a type of imaging scan) to measure this inflammation. You might be able to join if you are between 18 and 45 years old and are a nicotine vaper, cannabis vaper, or a healthy non-smoker. The main goal is to measure lung inflammation using the [18F]NOS PET/CT scan, with results expected after 3 years. The study's current status is unclear, and it plans to enroll 100 participants.

Study design

This is an interventional study, meaning participants will receive a specific intervention. It plans to enroll 100 participants.

What's involved

You would undergo one experimental [18F]NOS PET/CT scan, which includes images of your chest/torso (lungs) and a short image of your brain.

Compensation

Not stated in the trial record.

Follow-up

Lung inflammation will be measured at 3 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.