Submaximal Angioplasty for Intracranial Atherosclerotic Stenosis
This study is looking at a procedure called submaximal balloon angioplasty for people who have had a recent, non-severe stroke caused by a narrowing of a blood vessel in the brain (intracranial atherosclerotic stenosis). This procedure uses a balloon catheter to gently widen the narrowed blood vessel, aiming to improve blood flow. You might be able to join if you are between 30 and 90 years old, have had a recent stroke (within 30 days) due to a 70-99% blockage in a brain artery, and show signs of reduced blood flow to that area. The main goal of this study is to see how safe submaximal balloon angioplasty is within 30 days of the procedure. The study is currently unclear on its recruitment status and plans to enroll 159 participants.
- Study design
- This is a single-arm, open-label study planning to enroll 159 participants. It will assess the safety of submaximal balloon angioplasty.
- What's involved
- You would receive the submaximal balloon angioplasty intervention along with intensive medical therapy. The primary safety is measured at 30 days.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study will estimate the risk of subsequent stroke at one year and examine the durability of the angioplasty over follow-up.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis
At a glance
Conditions
NCT03729817
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Case Western Reserve University
Cleveland, Ohiostudy coordinator listed
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Sepideh Amin-Hanjani, MD · PRINCIPAL_INVESTIGATOR · Case Western Reserve University
- Adnan Siddiqui, MD · PRINCIPAL_INVESTIGATOR · University at Buffalo
- Tanya Turan, MD · PRINCIPAL_INVESTIGATOR · Medical University of South Carolina
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Procedural Safety30 days
Any stroke (ischemic or hemorrhagic), or death, within 30 days following submaximal angioplasty