C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience) for Cancer Survivors

This study, called C.A.P.A.B.L.E., is testing a 12-week high-intensity functional training program (CrossFit®) for adult cancer survivors. The goal is to see if this program can improve your physical abilities, body composition, and quality of life more than current guidelines. Researchers will also look at how many people join and complete the program, and what factors might make it harder for people to participate. You can join if you are 18 or older, have been diagnosed with any cancer, and your doctor says you are cleared to participate. The study aims to measure changes in your functional performance over 12 weeks. The current status of this study is unclear.

Study design
This is an interventional study with a planned enrollment of 500 participants. It is a pilot study to help refine methods for a larger study.
What's involved
You would participate in a 12-week high-intensity functional training program. You will complete weekly surveys and monthly physical assessments.
Compensation
Not stated in the trial record.
Follow-up
Your functional performance will be measured at the beginning and again at 12 weeks.

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NCT03750981

C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience)

Recruiting
NAAges 18+InterventionalTreatment
Barbara Ann Karmanos Cancer Institute
~500 participants
Updated 2025-11-06 on ClinicalTrials.gov
What's tested:12 week pilot intervention study.

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Enrollment rates
Measured over Baseline
+14 more outcomes measured
Cancer Survivors
1 sites across 1 states
Michigan1
  • Jennifer Beebe-Dimmer, MPH, PhD. · PRINCIPAL_INVESTIGATOR · Barbara Ann Karmanos Cancer Institute

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Eligibility criteria

Inclusion

Aged 18 years or older at time of program recruitment
Diagnosed with any cancer
Cleared from their physician to participate in the program (We assume that most patients will have completed treatment, however if a patient is currently under treatment, this should be their oncologist. If the patient is not currently undergoing treatment, this could be primary care physician or oncologist).
Available transportation to and from the facility on session days

Exclusion

Widely metastatic cancers to the brain or bone may be excluded.
  • Enrollment ratesBaseline

    Enrollment rates will be calculated among those who respond to notices about the study and adherence to the program among those who enroll and to describe reported barriers to participation among respondents who do not ultimately enroll

  • Change in functional performance and variability in functional performance among adult cancer survivors enrolled in a high-intensity functional training programBaseline to 12 weeks

    Physical measures of strength will be assessed by a certified trainer. To assess strength improvements deadlifts (lifting weights from floor to waist) will be performed in 10 lb. increments. A circuit will also be done with strength measures including sit ups and push ups.

  • Change in functional performance and variability in functional performance among adult cancer survivors enrolled in a high-intensity functional training programBaseline to 12 weeks

    Physical measures of flexibility will be assessed by a certified trainer. To assess flexibility sit ups, squats and push up level (floor, knees, on an elevated bar, etc) will be recorded.

  • Change in functional performance and variability in functional performance among adult cancer survivors enrolled in a high-intensity functional training programBaseline to 12 weeks

    Physical measures of cardiovascular strength will be assessed by a certified trainer. To assess cardiovascular strength maximum effort on a stationary bike will be recorded. Additionally, in the circuit, a maximum effort on a rowing machine will be recorded.

  • Change in self-reported health-related quality of life (HRQOL) and variability using the FACT questionnaireBaseline to 12 weeks

    Quality of Life will be measured using the Functional Assessment of Cancer Therapy: General (FACT), developed by Dr. David Cella. The FACT-G is 27 items assessing physical, social/ family, emotional and functional well-being. The survey uses a five-point scale from 0 (not at all) to 4 (very much). Scoring the FACT-G is performed through a sum of item scores. Higher scores indicate a better health state.

  • Change in Body CompositionBaseline to 12 weeks

    Changes in weight in kg

  • Change in Body CompositionBaseline to 12 weeks

    Changes in body fat percentage

  • Change in Body CompositionBaseline to 12 weeks

    Changes in visceral fat percentage

  • Change in Body CompositionBaseline to 12 weeks

    Changes in muscle mass percentage

  • Change in Body CompositionBaseline to 12 weeks

    Changes in body mass index (BMI) - Weight and height will be combined to report BMI in kg/ m2

  • Change in Body CompositionBaseline to 12 weeks

    Changes in resting metabolism value

  • Change in MotivationBaseline to 12 weeks

    Motivation to exercise will be collected via a survey

  • Satisfaction with the Program12 weeks

    Satisfaction with the program will be collected via a survey

  • Program Adherence12 weeks

    Program adherence will be calculated based on how many sessions each participant attended in the 13 week program, 36 session design.

  • HeightBaseline

    Height will be collected in meters to use in the calculation of Body Mass Index