This study aims to understand if people with chronic pain and fatigue, such as those with Fibromyalgia, Chronic Fatigue Syndrome, or Multiple Sclerosis, have higher levels of brain inflammation (neuroinflammation) compared to healthy individuals. Researchers will use a special imaging technique called DPA-714 PET/MRI. This involves a small amount of a radioactive tracer called [F-18]DPA-714, which helps to visualize activated brain cells (microglia/macrophages) that are involved in inflammation. The study is looking for 120 participants, including healthy volunteers and individuals aged 18 to 65 with these conditions. The main goal is to see if there's a difference in neuroinflammation levels between these groups, measured over three years. The current status of this study is unclear.

Study design

This interventional study plans to enroll 120 participants. It will compare neuroinflammation levels in healthy volunteers to those with specific chronic pain and fatigue conditions.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

Neuroinflammation will be measured at 3 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.