Observational Study of Skull Base Tumors

This is an observational study looking at skull base tumors. Researchers want to understand the biology of these tumors to find new ways to treat them. They will analyze biological samples and genetic material from people diagnosed with a skull base tumor. The study aims to identify new features that could help doctors better categorize tumors, predict how they might respond to treatment, and create more personalized treatment plans. They will also compare primary tumors (first tumors) with recurrent tumors (tumors that come back) to see what changes happen after surgery, chemotherapy, or radiation. The main goal is to track how long patients live (overall survival) over an average of 10 years.

Study design
This is an observational study with a planned enrollment of 4000 participants. It is not a treatment study, but rather focuses on understanding the disease.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Patient overall survival will be measured through study completion, an average of 10 years.

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NCT03759717

Molecular and Cellular Characterization of Skull Base Tumors

Recruiting
Not specifiedAll AgesObservational
University of Pittsburgh
~4,000 participants
Updated 2025-09-22 on ClinicalTrials.gov
What's tested:Observation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient overall survival will be measured and reported.
Measured over Through study completion, an average of 10 years
Skull Base Neoplasm
Cellular Pathology
1 sites across 1 states
Pennsylvania1
  • Paul Gardner, MD · PRINCIPAL_INVESTIGATOR · Associate Professor

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Eligibility criteria

Inclusion

Diagnosis of a skull base tumor

Exclusion

Insufficient tumor sample at time of resection
  • Patient overall survival will be measured and reported.Through study completion, an average of 10 years

    There will be one outcome measure: overall survival.