Back to search results

Developing Fast Pediatric Imaging for Low-grade Gliomas

This study is testing a new software technology called "wave-CAIPI" for Magnetic Resonance Imaging (MRI) systems. The goal is to make MRIs better at measuring brain tumor tissue, specifically for people with Pediatric Low-grade Gliomas (a type of brain tumor). Researchers want to improve how clear and efficient MRI images are. You might be able to join if you are an infant, child, or adult diagnosed with Low-grade Glioma, or if you are a healthy volunteer. The study aims to validate the "wave-CAIPI" technology over two years. The current status of this study is unclear, and it plans to enroll 300 participants.

Study design
This is an interventional study with a planned enrollment of 300 participants. It is testing a new imaging technology called wave-CAIPI.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, Wave-CAIPI validation, will be measured at 2 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03761121

Developing Fast Pediatric Imaging

Recruiting
NAAges 0+InterventionalDiagnostic
Boston Children's Hospital
~300 participants
Updated 2025-12-12 on ClinicalTrials.gov
What's tested:Wave-CAIPI

At a glance

Recruiting sites
3 of 3 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Wave-CAIPI validation
Measured over 2 years

Conditions

Pediatric Low-grade Gliomas

Explore related trials

Low Grade Glioma

NCT03761121

Where you'd take part

This study runs at 3 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Boston Children Hospital

    Boston, Massachusettsstudy coordinator listed

    Recruiting

  • Dana Farber Cancer Institute

    Boston, Massachusettsstudy coordinator listed

    Recruiting

  • Massachusetts General Hospital

    Boston, Massachusettsstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Kawin Setsompop, PhD · PRINCIPAL_INVESTIGATOR · Boston Children Hospital/ Massachusetts General Hospital

Who to contact

Kawin Setsompop, PhD
[email protected]
617-669-6640
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Infants, children and adults who have been diagnosed with Low Grade Glioma
Healthy volunteers - Children from age 0 to adults with no upper age limit or;
Diagnosed with LGG and being treated at DFCI;

Exclusion

Electrical implants such as cardiac pacemakers or perfusion pumps;
Ferromagnetic implants such as aneurysm clips, surgical clips, prosthesis, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants;
Ferromagnetic objects such as jewelry or metal clips;
Women of childbearing age who are seeking to become pregnant, who are breastfeeding, or who suspect they may be pregnant;
Pre-existing medical conditions including a likelihood of developing seizures or claustrophobic reactions;
Any greater than normal potential for cardiac arrest

What this trial measures

  • Wave-CAIPI validation2 years

    The outcome measure for this project will be that the rapid scan from Wave-CAIPI can provide equivalent diagnostic quality to that of standard clinical acquisitions which is performed at much slower speed. This will be assess using visual qualitative assessment by experienced radiologists on the project.