Study on Sleep Deprivation, Naps, and Emotional Processing

This study is looking at how a night of sleep deprivation and a daytime nap affect your emotions and memory. Researchers want to understand how not getting enough sleep changes how you process emotional information and if a nap can help reverse these effects. They will compare people who are sleep deprived for a whole night with those who get undisturbed sleep. After a night of sleep deprivation, some participants will have the chance to take a two-hour nap. The study will measure how accurately you recognize emotions, how strongly you feel them, and how well you remember emotional information. They will also look at your attention levels. You can join if you are between 18 and 35 years old, have normal vision, and are willing to avoid alcohol and recreational drugs during the study. The study aims to enroll 100 participants, but its current status is unclear.

Study design
This is an interventional study planning to enroll 100 participants to compare the effects of sleep deprivation and recovery sleep.
What's involved
You would be sleep deprived for an entire night, and some participants will have a 2-hour nap opportunity after that night. You will also need to refrain from alcohol and recreational drugs during the study.
Compensation
Not stated in the trial record.
Follow-up
Measurements will be taken between 1 and 24 hours after the interventions.

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NCT03767426

The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity

Recruiting
NAAges 18–35InterventionalBasic science
Beth Israel Deaconess Medical Center
~100 participants
Updated 2024-08-06 on ClinicalTrials.gov
What's tested:Sleep DeprivationDaytime nap

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Morphed Face Accuracy and Intensity
Measured over 1-24 hours
+2 more outcomes measured
Sleep Deprivation
Sleep
1 sites across 1 states
Massachusetts1
  • Tony Cunningham, PhD · PRINCIPAL_INVESTIGATOR · Beth Israel Deaconess Medical Center

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Eligibility criteria

Inclusion

willing and able to follow the protocol
willing to refrain from alcohol and recreational drugs for the duration of the protocol
normal or corrected to normal vision is required

Exclusion

self-reported sleep disturbances
left-handedness or ambidexterity
a history of mental illness or neurological disorder
the use of any drugs that could affect either sleep or cognitive functioning (e.g., sleeping pills or antidepressants)
  • Morphed Face Accuracy and Intensity1-24 hours

    Participants are asked to identify and rate emotional intensity of ambiguous emotional faces (happy, sad, angry) that have been morphed with neutral faces. Scores for each emotional domain will be calculated as (i) accuracy score (number of faces correctly identified over total faces seen), and (ii) average emotional intensity rating. Task will be completed at baseline, post-sleep/sleep deprivation, and post-nap/no nap, and within-subject comparisons will determine how interventions impact emotional perception.

  • Emotional Memory Tradeoff Memory Score12-24 hours

    Following sleep or sleep deprivation, participants will complete emotional memory tradeoff recognition task at two time points, separated by a nap or wakefulness. Corrected hit rate will be calculated for negative and neutral scene components as the percentage of correctly identified "old" objects/backgrounds minus percentage of false alarms ("new" pictures marked as "old")

  • Psychomotor vigilance task lapse rate1-24 hours

    The absolute number of trials in a 5-min test period on which the participant fails to responds with 500ms is calculated as the lapse rate.