EDRN Prostate MRI Biomarker Study for Prostate Cancer

This study is looking at how well prostate MRI (magnetic resonance imaging) works compared to, or in addition to, standard lab tests like PSA (prostate-specific antigen) in men who might have prostate cancer. Researchers want to see if adding an MRI can help doctors better identify significant prostate cancer. You might be able to join if you are a man, 18 or older, and are scheduled for a prostate biopsy because doctors suspect you have prostate cancer. The main goal is to see if adding an MRI can improve the accuracy of detecting high-grade prostate cancer by 10% over two years. The study's current status is unclear.

Study design
This is an observational study planning to enroll 950 men. It compares prostate MRI with laboratory biomarkers.
What's involved
You would need to have a prostate MRI and provide blood and urine samples. You must also be scheduled for a prostate biopsy as part of your routine care.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome of clinically significant prostate cancer will be measured at 2 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03784924

EDRN Prostate MRI Biomarker Study

Recruiting
Not specifiedAges 18+Observational
University of Michigan
~950 participants
Updated 2026-08-17 on ClinicalTrials.gov
What's tested:MRI prostate

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Clinically significant prostate cancer
Measured over 2 years
PSA
Prostate Cancer
1 sites across 1 states
Michigan1
  • John T Wei, MD, MS · PRINCIPAL_INVESTIGATOR · University of Michigan

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Men with suspected but undiagnosed prostate cancer
To be scheduled/scheduled for biopsy as routine clinical care

Exclusion

Inability to obtain blood and urine per SOP or conduct an attentive DRE
Unable to undergo/tolerate a prostate MRI or failure to conduct the MRI
Prior diagnosis of prostate cancer
Prior prostate MRI unless being used as Index MRI (in this case index MRI can be one year prior to consent date)
Participating in clinical trial for prostate disease
Prior prostate surgery such as TURP, TUNA, TUMT, HOLEP, REZUM, UROlift
Prior PCA3, TMPRSS2:erg or MIPS panel performed for clinical purpose
  • Clinically significant prostate cancer2 years

    Pathologic diagnosis of prostate cancer with at least Gleason 7 or worse cancer grade on a needle biopsy