The EXPLORE MG Registry for Myasthenia Gravis

This study, called the EXPLORE MG Registry, aims to create a collection of biological samples and health information from people with Myasthenia Gravis (MG) at Yale University. Researchers will collect blood samples to better understand MG, including how it progresses, how it's treated, and its impact on health. The goal is to build a resource for current and future research projects to answer important questions about MG. You may be able to join if you are an adult diagnosed with Myasthenia Gravis and receive care or research interventions at the Yale Department of Neurology. The main goal of this study is to successfully collect blood samples, which will be reported at the end of the 8-year sample collection period. The current recruitment status is unclear.

Study design
This is an observational study planning to enroll 800 participants. It is not a drug trial but a registry to collect information and samples.
What's involved
If you join, you will have approximately 100 cc (less than 1/2 cup) of blood drawn. The study will collect peripheral blood, stool, and information about your disease status, course, and treatment.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint for successful blood draws is measured at 8 years, indicating a long-term collection period.

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NCT03792659

The EXPLORE MG Registry for Myasthenia Gravis

Recruiting
Not specifiedAges 18+Observational
Yale University
~800 participants
Updated 2025-11-28 on ClinicalTrials.gov
What's tested:Blood Sample Draw

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The number of successful blood draws will be reported at the conclusion of the sample collection
Measured over 8 years
Myasthenia Gravis
1 sites across 1 states
Connecticut1
  • Richard Nowak, MD, MS · PRINCIPAL_INVESTIGATOR · Assistant Professor, Yale University

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Eligibility criteria

Inclusion

Adult patients diagnosed with Myasthenia Gravis presenting to the Yale Department of Neurology for clinical care or research interventions will be invited to donate their biological specimens/clinical data.
  • The number of successful blood draws will be reported at the conclusion of the sample collection8 years

    Successful Collection of Blood