Observational Study of Iris Tumors

This study is observing iris tumors to better understand them. Researchers are using a special imaging technique called OCT angiography to look at blood vessels in the eye. They will compare images from healthy eyes to eyes with different types of iris tumors. The main goal is to measure the thickness of tumors in benign (non-cancerous) versus malignant (cancerous) iris lesions after 6 months. You may be able to join if you are 18 or older and have a diagnosis of an iris tumor, or if you have healthy eyes without any iris problems. The study is currently unclear on its recruitment status.

Study design
This is an observational study comparing OCT angiography data from healthy eyes to eyes with iris tumors. It plans to enroll 100 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Tumor thickness will be measured at 6 months.

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NCT03809585

Observational Study of Iris Tumors

Recruiting
Not specifiedAges 18+Observational
Oregon Health and Science University
~100 participants
Updated 2025-09-09 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Tumor Thickness in Benign vs Malignant Iris Lesions
Measured over 6 months
Iris Tumor
1 sites across 1 states
Oregon1
  • David Huang, MD, PhD · PRINCIPAL_INVESTIGATOR · Oregon Health and Science University

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Eyes with diagnosis of melanotic or amelanotic iris tumors
Eyes without iris defects or lesions

Exclusion

Inability to give informed consent
Inability to maintain stable fixation for OCT imaging
Inability to commit to required study visits
Eyes with concurrent retinal diseases, glaucoma, or conditions that in the opinion of the investigators might affect iris circulation
Mature cataracts if found to limit visual potential to worse than 20/40
  • Tumor Thickness in Benign vs Malignant Iris Lesions6 months

    OCT/OCTA will be used to compare tumor thickness measurements against the conventional Ultrasonic Biomicroscopy (UBM) device. Tumor thickness will be measured in millimeters, and growth of 0.5 mm or greater will be used to differentiate malignant from benign lesions.