Post-Op Pain Control for Prophylactic Intramedullary Nailing

This study is looking at ways to manage pain after surgery for people with bone metastases, lymphoma, or multiple myeloma who are having a prophylactic intramedullary nailing procedure. This surgery places a rod in the thigh bone to prevent future fractures. The study compares using the pain medication Ketorolac (an NSAID) along with standard opioid pain medicines (like oxycodone-acetaminophen or morphine) to using only opioid pain medicines. The main goal is to see if adding Ketorolac can reduce the amount of opioid medication needed for pain control in the first 14 days after surgery. You may be eligible if you are 18 or older, have a bone lesion in your thigh bone, and are scheduled for this specific surgery. The study plans to enroll 60 participants, but its current status is unclear.

Study design
This interventional study plans to enroll 60 participants to compare two different pain management approaches after surgery. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Opioid medication use will be measured for 14 days after surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03823534

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Recruiting
PHASE3Ages 18+InterventionalTreatment
St. Louis University
~60 participants
Updated 2026-04-22 on ClinicalTrials.gov
What's tested:KetorolacNormal salineAcetaminophenOxycodone AcetaminophenMorphineHydrocodone/Acetaminophen

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Milligram Morphine Equivalent (MME) of Opioid Medications Utilized
Measured over Post-op days 1-14
Bone Metastases
Lymphoma
Multiple Myeloma
Opioid Use
Pain

NCT03823534

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Saint Louis University

    St Louis, Missouristudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • David Greenberg, MD · PRINCIPAL_INVESTIGATOR · St. Louis University

Opens a ready-to-send draft in your own email app — review before sending.

  • Milligram Morphine Equivalent (MME) of Opioid Medications UtilizedPost-op days 1-14

    Measure the effect of post-op ketorolac on the concurrent use of opioid pain medications during post-op days 1-14 following prophylactic IMN of the femur compared to patients treated only with opioids.