Long-Term Health of Pediatric Cushing Disease Survivors
This observational study is looking at the long-term health of people who had Cushing disease (a condition where your body makes too much cortisol due to a pituitary tumor) when they were children or teenagers. Even after successful treatment, some problems from high cortisol levels might continue. Researchers want to understand these lasting effects, especially how body mass index (BMI) changes over time compared to the general population. You may be eligible if you are between 10 and 42 years old, were diagnosed with Cushing disease before age 21, and have been successfully treated.
- Study design
- This is an observational study aiming to include 600 participants. It is not a treatment study, but rather observes health outcomes over time.
- What's involved
- Participants will be screened with a medical history and complete an online survey about their or their child's physical and mental health.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study will track differences in body mass index z-score at baseline, 5, 10, 15, and 20 years.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Long-Term Follow-Up of Survivors of Pediatric Cushing Disease
At a glance
Conditions
NCT03831958
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
National Institutes of Health Clinical Center
Bethesda, Marylandstudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Deborah P Merke, M.D. · PRINCIPAL_INVESTIGATOR · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Difference in body mass index z-score of subjects previously treated for Cushing disease compared to general populationbaseline, 5, 10, 15, 20 years
The primary outcome measure of the study is the difference in the Body Mass Index (BMI) z-score of the patients previously treated for pediatric CD compared to the general population, as calculated by data derived from the NHANES study.