Sensory Symptoms in Tourette Syndrome Study

This observational study is looking at how sensory symptoms, or feelings and sensations, change over time in people with Tourette Syndrome. Researchers are not testing a specific drug or intervention. Instead, they want to understand the extent and variety of non-motor features (symptoms not related to movement) of Tourette Syndrome, like premonitory urges (feelings before a tic), sensory experiences, attention issues, obsessive-compulsive tendencies, anxiety, and depression. You can join if you are 18 or older, can complete questionnaires in English, and have a diagnosis of Tourette Syndrome or a chronic tic disorder. The study aims to understand these symptoms by measuring your Sensory Perception Quotient score annually for up to two years.

Study design
This is an observational study planning to enroll 214 participants. It will collect information about symptoms and conditions related to Tourette Syndrome over time.
What's involved
You would complete a series of questionnaires about your symptoms and quality of life annually. These can be done online or on paper.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for two years, with assessments at enrollment, one year, and two years.

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NCT03851484

Sensory Symptoms in Tourette Syndrome

Recruiting
Not specifiedAges 18+Observational
Vanderbilt University Medical Center
~214 participants
Updated 2026-03-13 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Baseline Sensory Perception Quotient score, short form
Measured over Initial assessment at enrollment (time zero)
+2 more outcomes measured
Tourette Syndrome
2 sites across 1 states
Tennessee2
  • David A Isaacs, MD, MPH · PRINCIPAL_INVESTIGATOR · Vanderbilt University Medical Center

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Eligibility criteria

Inclusion

18 years of age or older
Ability to provide informed consent and answer self-report questionnaires independently in English
Diagnosis of Tourette syndrome (TS), chronic motor tic disorder, or chronic vocal tic disorder

Exclusion

History of psychotic disorder
History of significant neurologic disorder (e.g., stroke) other than TS or another chronic tic disorder
  • Baseline Sensory Perception Quotient score, short formInitial assessment at enrollment (time zero)

    Validated instrument assessing anomalous sensory experiences. Scale consists of 35 items screening patients for hyper- or hypo-sensitivity to each of the sensory domains (touch, sight, sound, smell, and taste). Each scale item is a statement to which participants provide a ranking: 0 = strongly agree 1. = agree 2. = disagree 3. = strongly disagree The minimum score on the short from is 0; the maximum score is 140. Higher scores indicate more abnormal sensory experiences.

  • Change in Sensory Perception Quotient score, short form at 1 year1 year

    Validated instrument assessing anomalous sensory experiences. Scale consists of 35 items screening patients for hyper- or hypo-sensitivity to each of the sensory domains (touch, sight, sound, smell, and taste). Each scale item is a statement to which participants provide a ranking: 0 = strongly agree 1. = agree 2. = disagree 3. = strongly disagree The minimum score on the short from is 0; the maximum score is 140. Higher scores indicate more abnormal sensory experiences.

  • Change in Sensory Perception Quotient score, short form at 2 years2 years

    Validated instrument assessing anomalous sensory experiences. Scale consists of 35 items screening patients for hyper- or hypo-sensitivity to each of the sensory domains (touch, sight, sound, smell, and taste). Each scale item is a statement to which participants provide a ranking: 0 = strongly agree 1. = agree 2. = disagree 3. = strongly disagree The minimum score on the short from is 0; the maximum score is 140. Higher scores indicate more abnormal sensory experiences.