Preventing Atrial Fibrillation After Heart Surgery
This study is looking for people having their first open-heart surgery for conditions like coronary artery bypass graft (CABG) or valve repair/replacement. You must have a normal heart rhythm and no past history of atrial fibrillation (a type of irregular heartbeat). The study aims to see if a test during surgery, called Intraoperative Rapid Atrial Pacing, can predict who might get postoperative atrial fibrillation (POAF). If this test shows you are likely to get POAF, you might then receive Amiodarone, a medication given by injection, to help prevent it. The main goal is to see if this approach can lower the number of patients who develop POAF within 30 days after surgery. The study plans to enroll 600 participants, but its current status is unclear.
- Study design
- This interventional study plans to enroll 600 participants. During surgery, a test will determine if you are likely to develop atrial fibrillation, and if so, you will be randomly assigned to receive Amiodarone or no treatment.
- What's involved
- During your open-heart surgery, a short test will be performed on your heart. If the test shows you are likely to develop atrial fibrillation, you may receive Amiodarone until you are discharged from the hospital.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your heart rhythm will be monitored for 30 days after surgery to see if you develop postoperative atrial fibrillation.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone Treatment
At a glance
Conditions
NCT03868150
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Stanford University
Stanford, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Anson Lee, MD · PRINCIPAL_INVESTIGATOR · Stanford University
Who to contact
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Inclusion
Exclusion
What this trial measures
- Decreasing the incidence of Post-Operative Atrial Fibrillation for Cardiac Surgery Patients30 days
Identify predictors of developing atrial fibrillation in the hope of decreasing post-operative length of stay, the need for anticoagulation, decrease risk of stroke, DVT, and bleeding