Clinical Pre-screening for Ovarian Cancer with DRP®

This study is looking at a tool called Drug Response Predictor® (DRP®) to see if it can help predict which investigational cancer drugs might work best for you if you have ovarian cancer. The DRP® uses a sample of your tumor tissue to make these predictions. You may be able to join if you are a woman, at least 18 years old, have epithelial ovarian cancer that has come back within six months of platinum-based chemotherapy (platinum-resistant) or if you cannot receive platinum-based chemotherapy. You should also have received no more than one prior treatment for your platinum-resistant or platinum-ineligible disease. The main goal is to see if the DRP® can identify patients who are likely to respond to investigational cancer drugs, with results measured for up to two years.

Study design
This is an observational study, meaning researchers will collect information without giving you a specific treatment. It plans to include 60 participants.
What's involved
Your archival tumor tissue (FFPE) from your original tumor or metastatic tissue will be collected. The study does not specify any other visits, procedures, or tests.
Compensation
Not stated in the trial record.
Follow-up
The study aims to identify patients likely to be sensitive to investigational drugs, with results measured for up to two years.

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NCT03877796

Clinical Pre-screening Protocol for Ovarian Cancer

Recruiting
Not specifiedAges 18+Observational
Allarity Therapeutics
~60 participants
Updated 2026-07-30 on ClinicalTrials.gov
What's tested:Drug Response Predictor® (DRP)

At a glance

Recruiting sites
9 of 9 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Identification of ovarian cancer patients with high likelihood of being sensitive to investigational cancer drug
Measured over up to 2 years
Ovarian Cancer
9 sites across 9 states
Florida1
Georgia1
New Mexico1
New York1
Oklahoma1
Texas1
Washington1
Scotland1

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Eligibility criteria

Inclusion

Patients with histological confirmed epithelia ovarian cancer
Patients must have platinum-resistant disease, defined as progression within 6 months after the last dose of platinum-based chemotherapy, or are platinum ineligible.
Patients have received no more than one prior line of therapy in the platinum resistant or platinum ineligible setting
FFPE tumor tissue available

Exclusion

Patients who have platinum-refractory disease, defined as progression during the last platinum-based chemotherapy.
Other malignancy with exception of any stage I and II cancer that is deemed cured by the Investigator
  • Identification of ovarian cancer patients with high likelihood of being sensitive to investigational cancer drugup to 2 years

    based on FFPE ovarian cancer tissue