L-citrulline for Overweight Adults with Late-Onset Asthma
This study is looking at whether L-citrulline, a natural substance, can help adults with asthma who are also overweight and developed asthma later in life. These individuals often have asthma symptoms that are hard to control with usual inhaled medications. The study will compare L-citrulline to a matching placebo (an inactive substance) over 7 weeks. Researchers will measure changes in your asthma control using questionnaires like the Asthma Control Questionnaire and Asthma Control Test to see if L-citrulline helps improve your symptoms. You may be able to join if you are between 18 and 65 years old, have a doctor's diagnosis of asthma, and have a body mass index (BMI) of 30 or higher. The current status of this study is unclear.
- Study design
- This is an interventional study planning to enroll 60 participants. It compares L-citrulline to a matching placebo.
- What's involved
- You would receive either L-citrulline or a placebo orally (mixed with water) for 7 weeks. Your asthma control will be measured through study completion, up to 32 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your asthma control will be measured through study completion, up to 32 weeks after starting treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Supplementing L-citrulline to Overweight Late Asthma oNset Phenotypes
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Fernando Holguin, MD, MPH · PRINCIPAL_INVESTIGATOR · University of Colorado Denver- Anschutz Medical Campus
Who to contact
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What this trial measures
- Change in Asthma Control QuestionnaireThrough study completion, up to 32 weeks
to determine L-citrulline efficacy, reduction in questionnaire scores determined by administering the questionnaires before, mid-way, and after during each treatment phase to see if there's a change in scores.
- Change in Asthma Control TestThrough study completion, up to 32 weeks
To determine L-citrulline efficacy, reduction in questionnaires scores determined by administering the questionnaires before, mid-way, and after during each treatment phase to see if there's a change in scores.