Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)
This study, called RAATE, is looking at how physical activity can help reduce the risk of Alzheimer's disease in older African American adults. It will compare a physical activity program to a program focused on general health topics and light stretching. The researchers want to see if physical activity can improve memory and thinking skills (cognitive function) and brain health related to Alzheimer's. They are also looking at how physical activity affects other body functions. You might be able to join if you are an African American adult, 60 years or older, and not currently doing regular physical activity. The study is currently unclear on its recruitment status and plans to enroll 125 participants.
- Study design
- This is an interventional study that plans to enroll 125 participants. Participants will be randomly assigned to either a physical activity program or a successful aging seminar group.
- What's involved
- Participants will attend group sessions. The study measures changes in memory and executive function at the start, 24 weeks, and 52 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for at least 52 weeks after the start of the study.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)"
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Robert L Newton, Jr., PhD · PRINCIPAL_INVESTIGATOR · Pennington Biomedical Research Center
- Owen L Carmichael, PhD · PRINCIPAL_INVESTIGATOR · Pennington Biomedical Research Center
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Change in episodic memoryBaseline, 24 weeks, 52 weeks
The Rey Auditory Verbal Learning Test (RAVLT) is a common neuropsychological tool used to evaluate episodic memory. The RAVLT involves providing participants with 15 unrelated words and asking them to recall the word list. There are 5 trials designed to determine short-term memory and then a 30 minute delay to assess long-term memory. The total words correct in both the short- and long-term trials are used as outcome measures.
- Change in executive functionBaseline, 24 weeks, 52 weeks
The NIH Toolbox Executive Function subdomain consists of the Flanker Inhibitory Control and Attention Test and the Dimensional Change Card Sort Test. The Flanker test is a measure of one's ability to inhibit attention to irrelevant conditions. Participants must identify the direction of a central visual stimuli amongst flanking stimuli either congruent or incongruent with the central stimuli. There are 40 trials and scores range from 0 - 10. The Card Sort is a measure of the ability to shift attention based on rules. Participants must match a target visual stimuli to either a color or word stimuli and this matching shifts during the assessment.