This study is looking at how a medicine called Pegloticase (Krystexxa) affects blood pressure in young men with type 2 diabetes (T2D) that started in their youth. We know that high uric acid levels are common in young men with youth-onset T2D and can be linked to high blood pressure and kidney problems. This study wants to see if lowering uric acid with a single dose of Pegloticase can improve blood pressure. To join, you must be a man between 18 and 25 years old, have youth-onset T2D, and have high uric acid levels (serum uric acid ≥ 5 mg/dl). The study will measure your blood pressure at the start and one week after treatment to see if it changes. The current status of this study is unclear.

Study design

This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 11 participants.

What's involved

You would receive a single infusion of Pegloticase over two hours in an outpatient clinic and be monitored afterward. Your blood pressure will be measured at the start and one week after treatment.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for at least one week after treatment, with blood pressure measurements taken at baseline and one week post-treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.