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Fractionated Laser Resurfacing for Actinic Keratoses and Skin Cancer Prevention

This study is looking at how well Fractionated Laser Resurfacing (a rejuvenating laser that makes tiny holes in the very superficial part of the skin) can protect older adults from developing actinic keratoses (rough, scaly patches on the skin caused by sun exposure) and non-melanoma skin cancers. Researchers want to see if this treatment can restore the skin's normal response to sunlight. You might be able to join if you are at least 60 years old, have fair skin, and have been diagnosed with actinic keratoses in the past six months. The study will measure changes in the number of actinic keratoses and non-melanoma skin cancers over up to five years to see if the treatment is effective. The current status of this study is unclear.

Study design
This is an interventional study planning to enroll 72 participants. The study is investigating the effects of Fractionated Laser Resurfacing.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for changes in actinic keratoses and non-melanoma skin cancers for up to 5 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03906253

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

Recruiting
NAAges 60+InterventionalPrevention
Wright State University
~72 participants
Updated 2026-07-17 on ClinicalTrials.gov
What's tested:Fractionated Laser Resurfacing

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change From Baseline in the Number of Actinic Keratosis due to FLR treatment.
Measured over up to 5 years
+1 more outcome measured

Conditions

Actinic Keratoses
Aging
Non-Melanoma Skin Cancer

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Actinic KeratosisSkin Carcinoma

NCT03906253

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Dayton VA Medical Center

    Dayton, Ohiono site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Jeffrey B Travers, MD, PhD · PRINCIPAL_INVESTIGATOR · Wright State University

Who to contact

Manager, Clinical Research Operations
[email protected]
937-245-7500
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Diagnosed with Actinic Keratosis within the past 6 months
At least 60 years of age, or older
Ability to comprehend procedures and risks versus benefits
Able to provide Informed Consent
Fair Skin (Fitzpatrick Type I or II)
Possess both Right and Left Forearms

Exclusion

Uncontrolled Diabetes Mellitus
Not able to comprehend procedures or risks versus benefits
Pregnant or nursing
Large tattoos on forearms
History of abnormal healing or scarring (i.e., keloids)
Any disease that gets worse while in the sun
Use of topical or oral anti-inflammatory medication or steroids
Allergy to lidocaine
Current use of photosensitizing medication

What this trial measures

  • Change From Baseline in the Number of Actinic Keratosis due to FLR treatment.up to 5 years

    Investigator will assess the number of actinic keratosis on both forearms.

  • Change From Baseline in the Number Non-Melanoma Skin Cancers due to FLR treatment.up to 5 years

    Investigator will assess the number of actinic keratosis on both forearms.