Thinking Zinc: A Study of Zinc Supplements on the Navajo Nation
This study, called "Thinking Zinc," is looking at whether taking a daily zinc supplement can help people living near abandoned uranium mines. These communities may be exposed to metals like uranium and arsenic, which can affect the immune system and overall health. The study will give participants Zinc Picolinate 15 Mg every day for six months. Researchers will measure metal levels, immune cell types (lymphocyte phenotyping), and inflammation markers (cytokine levels) at different times over nine months to see if the zinc supplement helps reduce the effects of metal exposure. You can join if you are between 21 and 64 years old, live in Blue Gap-Tachee, Arizona, or Red Water Pond Road Community, New Mexico, and are willing to provide blood and urine samples and take the supplement daily. The current status of the study is unclear.
- Study design
- This is an interventional study with a planned enrollment of 100 participants. The phase of the study is not specified.
- What's involved
- You would need to attend study visits on scheduled dates, provide blood and urine samples, and take a daily zinc supplement for six months.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for nine months, with measurements taken at 0, 3, 6, and 9 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Thinking Zinc: a Study of Zinc Supplements on the Navajo Nation
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Inclusion
Exclusion
What this trial measures
- Metal biomonitoring to compare change from baseline versus zinc supplementVisit 1 (0 months-baseline 1), Visit 2 (3 months-baseline 2), Visit 3 (6 months-zinc 1), Visit 4 (9 months-zinc 2)
urinary and serum metal levels to be measured by inductively coupled plasma mass spectrometry
- Lymphocyte phenotyping to compare change from baseline versus zinc supplementVisit 1 (0 months-baseline 1), Visit 2 (3 months-baseline 2), Visit 3 (6 months-zinc 1), Visit 4 (9 months-zinc 2)
Lymphocyte phenotypes will be measured in blood samples
- Cytokine level measurement to compare change from baseline versus zinc supplementVisit 1 (0 months-baseline 1), Visit 2 (3 months-baseline 2), Visit 3 (6 months-zinc 1), Visit 4 (9 months-zinc 2)
A cytokine panel will be used to measure levels of multiple cytokines in blood samples
- Autoantibody measurement to compare change from baseline versus zinc supplementVisit 1 (0 months-baseline 1), Visit 2 (3 months-baseline 2), Visit 3 (6 months-zinc 1), Visit 4 (9 months-zinc 2)
Autoantibody panel titers will be measured in blood samples