NCT03914664
Neural Correlates of Sensory Phenomena in Tourette Syndrome
Enrolling by Invitation
Not specifiedAges 18+ObservationalVanderbilt University Medical CenterInvestigator-initiated
~50 participants
Updated 2026-01-14 on ClinicalTrials.gov
What's tested:Electroencephalogram (EEG) testing procedureAutonomic function testing procedure
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Network oscillations in response to sensory stimuli
Measured over Baseline
+2 more outcomes measured
Conditions
Where it's being run
1 sites across 1 statesTennessee1
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Diagnosis of Tourette syndrome or other chronic tic disorder
≥ 18 years of age
Ability to complete survey instruments
English fluency (given that all scales are validated in English)
≥ 18 years of age AND age within 5 years of a participant in the TS arm of same biological sex (for purposes of age- and sex-matching)
Ability to complete survey instruments
English fluency (given that all scales are validated in English)
Exclusion
Use of anti-seizure medications, stimulants, or other psychotropic medications known to alter EEG signal
Recreational substance use within past 30 days
Any neurologic or psychiatric diagnoses
History of tics
Use of any psychotropic medications within the past 30 days
Recreational substance use within past 30 days
What this trial measures
- Network oscillations in response to sensory stimuliBaseline
Neural activity captured on EEG can be spectrally decomposed into various frequency constituencies. Neural activity in the gamma frequency range, so-called gamma band oscillations (GBOs), are associated with sensory processing and integration and are postulated to underlie sensory phenomena in TS.
- Heart rate variabilityBaseline
Change beat-to-beat variability in heart rate
- Electrodermal activity in response to sensory stimuliBaseline
Sweat response changes within 1-3 seconds of non-aversive sensory stimulus