Dietary Approaches to Stop Hypertension (DASH) Diet for Obesity
This study is looking at how different diets affect weight in women with obesity. Researchers want to see if a calorie-restricted DASH diet (Dietary Approaches to Stop Hypertension) or a calorie-restricted standard American diet can help with weight loss. They will also collect stool samples to look for changes in gut bacteria. The study aims to enroll 28 women, aged 19-65, who are non-Hispanic Black or White and have a Body Mass Index (BMI) of 30 or higher. To be considered successful, the study will measure changes in participants' weight at different time points over 42 days. The current status of this study is unclear.
- Study design
- This is a randomized controlled pilot study with 28 participants. You would be randomly assigned to one of two diet groups.
- What's involved
- You would follow a specific diet provided by the study for 4 weeks and visit the Bionutrition Unit daily. Fecal samples will be collected at multiple times before, during, and after the diet period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your weight will be measured up to 42 days after the start of the study.
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Modifying Diet to Improve Gut Microbiome
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Tiffany L Carson, PhD · PRINCIPAL_INVESTIGATOR · Moffitt Cancer Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Mean Weight Change of ParticipantsBaseline to day 28
Weight change as measured by a scale in kilograms at multiple time points will be calculated and averaged.
- Mean Weight Change of ParticipantsDay 28 to Day 42
Weight change as measured by a scale in kilograms at multiple time points will be calculated and averaged.
- Mean Weight Change of ParticipantsBaseline to day 42
Weight change as measured by a scale in kilograms at multiple time points will be calculated and averaged.
- Diet-specific changes in secondary bile acidBaseline to day 28
The investigators will calculate changes in cholic acid in milligrams.
- Diet-specific changes in secondary bile acidday 28 to day 42
The investigators will calculate changes in cholic acid in milligrams.
- Diet-specific changes in secondary bile acidbaseline to day 42
The investigators will calculate changes in cholic acid in milligrams.
- Diet-specific changes in inflammatory markerbaseline to day 28
The investigators will calculate changes in c-reactive protein in mg/L.
- Diet-specific changes in inflammatory markerday 28 to day 42
The investigators will calculate changes in c-reactive protein in mg/L.
- Diet-specific changes in inflammatory markerbaseline to day 42
The investigators will calculate changes in c-reactive protein in mg/L.
- Diet-specific changes in short chain fatty acidsbaseline to day 28
The investigators will calculate changes in acetic acid in mmol/L
- Diet-specific changes in short chain fatty acidsday 28 to day 42
The investigators will calculate changes in acetic acid in mmol/L
- Diet-specific changes in short chain fatty acidsbaseline to day 42
The investigators will calculate changes in acetic acid in mmol/L