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Transcranial Direct Current Stimulation for Post-Stroke Aphasia

This study is testing if combining transcranial direct current stimulation (tDCS) with speech-language therapy (SLT) can improve language skills for people with aphasia (difficulty with language after a stroke). Researchers are using a device called Soterix Medical 1x1 transcranial Direct Current Stimulator for Clinical Trials (1x1 tDCS-CT) to deliver either active stimulation to the left side of the brain or a sham (inactive) stimulation. The goal is to see if this combination helps people with aphasia, particularly with word-finding difficulties. You might be able to join if you are between 18 and 80 years old, had a single stroke on the left side of your brain at least 6 months ago, have post-stroke aphasia, and speak English as your native language. The study will measure success by looking at how well participants can name nouns.

Study design
This study involves 50 participants and compares active transcranial direct current stimulation (tDCS) with speech-language therapy (SLT) to sham (inactive) tDCS with SLT.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your ability to name nouns will be measured immediately after the first and second treatment phases, and again 10 weeks after the study ends.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03929432

Treatment Outcomes With tDCS in Post-Stroke Aphasia

Active, Not Recruiting
NAAges 18–80InterventionalTreatment
University of Arkansas
~50 participants
Updated 2026-07-01 on ClinicalTrials.gov
What's tested:Active Transcranial Direct Current Stimulation with SLTSham Transcranial Direct Current Stimulation with SLT

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in correct naming of nouns on Philadelphia Naming Test.
Measured over Immediately after 1st and 2nd treatment phases and at 10 follow up after study completion

Conditions

Aphasia

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Aphasia

NCT03929432

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansasno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Dana Moser, PhD, CCC-SLP · PRINCIPAL_INVESTIGATOR · University of Arkansas

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Presence of post-stroke aphasia
Single left hemisphere stroke etiology
At least 6 months post-stroke
Age range between 18 and 80 years old
Speak English as a native language
Adequate hearing and vision to complete the tasks

Exclusion

Severe auditory comprehension deficits (determined by pretest) (i.e., global aphasia, Wernicke's aphasia, transcortical sensory aphasia)
Inability to provide informed consent
Co-occurring history of neurological disease/disorder/injury (e.g., traumatic brain injury, right hemisphere stroke, dementia)
Co-occurring history of a major mental illness (e.g., schizophrenia, drug addiction, bipolar)
Clinical conditions contraindicated for MRI or tDCS (e.g., implanted electrical devices, claustrophobia, seizure disorder)
Positive pregnancy test (for females)

What this trial measures

  • Change in correct naming of nouns on Philadelphia Naming Test.Immediately after 1st and 2nd treatment phases and at 10 follow up after study completion

    Naming gains for untreated items.