Pilocarpine Use After Kahook Goniotomy for Glaucoma

This study is investigating if adding pilocarpine (a glaucoma medication) improves the success of combined cataract surgery with Kahook Dual Blade (KDB) for people with glaucoma or ocular hypertension (high eye pressure). The KDB procedure helps lower eye pressure by improving fluid drainage. Pilocarpine works by opening up the eye's drainage system. The study aims to see what percentage of patients experience lower eye pressure for up to one year after the procedure. You may be able to join if you are between 30 and 100 years old, have open-angle glaucoma or ocular hypertension, and are having this specific combined surgery at Montefiore Medical Center. You cannot have had previous eye surgeries. The current status of this study is unclear.

Study design
This is an interventional study with a planned enrollment of 142 participants. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for one year after the procedure to measure changes in intraocular pressure.

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NCT03933631

Pilocarpine Use After Kahook Goniotomy

Recruiting
PHASE3Ages 30+InterventionalTreatment
Montefiore Medical Center
~142 participants
Updated 2025-11-10 on ClinicalTrials.gov
What's tested:PilocarpinePrednisoloneOfloxacin

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of patients with lowering of intraocular pressure (IOP)
Measured over From baseline to 1 year following procedure
Glaucoma
2 sites across 1 states
New York2
  • Wen-Jeng (Melissa) Yao, MD · PRINCIPAL_INVESTIGATOR · Montefiore Medical Center

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Eligibility criteria

Inclusion

Patients with ocular hypertension or open angle glaucoma undergoing combined cataract surgery with KDB in a single surgical center at Montefiore Medical Center with a single provider

Exclusion

Patients with previous history of eye surgeries (including laser procedures)
  • Percentage of patients with lowering of intraocular pressure (IOP)From baseline to 1 year following procedure

    The percentage of patients who had a reduction in IOP of 20% or more from baseline will be summarized by study arm using descriptive statistics.