Observational Study on Globin Variants and Blood Disorders

This observational study aims to collect biological samples from people with blood disorders like sickle cell disease and malaria, as well as from healthy volunteers. Researchers want to better understand how changes in globin (a protein in red blood cells) affect these conditions and other diseases involving inflammation. You can join if you are 18-70 years old and are willing to provide samples like saliva, urine, or blood. The main goal is to gather these samples to support future research into blood disorders. This study is currently collecting samples, but its overall status is unclear.

Study design
This is an observational study planning to enroll 300 participants. It involves collecting biological samples without specific interventions.
What's involved
You will be screened with a medical history, physical exam, and blood and urine tests. You will give one or more samples over a period of up to 5 years.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03937817

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Recruiting
Not specifiedAges 18–70Observational
National Institute of Allergy and Infectious Diseases (NIAID)
~300 participants
Updated 2026-08-31 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Collect biological specimens (saliva, urine, blood, blood waste products, adipose tissue, bronchial brushing, and/or BAL)
Measured over Throughout study
Alpha and Beta Thalassemia
Sickle Cell Disease
Malaria
Human Physiology
1 sites across 1 states
Maryland1
  • Hans C Ackerman, M.D. · PRINCIPAL_INVESTIGATOR · National Institute of Allergy and Infectious Diseases (NIAID)

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  • Collect biological specimens (saliva, urine, blood, blood waste products, adipose tissue, bronchial brushing, and/or BAL)Throughout study

    Development and optimization of scientific assays and research of globin variants, sickle cell disease, malaria, or other related diseases.