Oral Iron for Children with Chronic Kidney Disease
This study is looking at how oral iron, specifically Ferrous Sulfate, affects children aged 1 to 21 years old who have chronic kidney disease (CKD) and mild anemia (low red blood cell count). You might be able to join if your child's kidneys aren't working as well as they should (estimated glomerular filtration rate or GFR less than 90) and they have mild anemia. The study will compare children who receive Ferrous Sulfate to those who don't, over a 3-month period. Researchers will measure changes in muscle strength and the amount of iron in the blood (transferrin saturation) to see if the treatment is helpful. The study plans to enroll 40 participants.
- Study design
- This is a pilot study that will randomly assign 40 participants to either receive oral iron (Ferrous Sulfate) or no iron therapy. The study will last for 3 months.
- What's involved
- Participants will receive oral iron (Ferrous Sulfate) daily for 3 months, or no iron therapy. Muscle strength, physical activity, and eating behavior will be measured at the beginning and end of the 3-month study period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 3 months, with measurements taken at the start and end of this period.
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Oral Iron in Children With Chronic Kidney Disease
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Oleh Akchurin, M.D. · PRINCIPAL_INVESTIGATOR · Weill Cornell College of Medicine
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Change in muscle strength0 and 3 months
Hand-grip strength measured by a dynamometer
- Change in the percentage of transferrin saturation in the participants' blood0 and 3 months
Transferrin saturation is a medical laboratory value, measured as a percentage. It is the value of serum iron concentration divided by the total iron-binding capacity. For instance, a value of 15% means that 15% of iron-binding sites of transferrin are being occupied by iron. Blood will be collected with the venopuncture used for clinically indicated blood tests at routine clinic visits