Neuromodulation for Septic Shock
This study is looking at a new way to treat septic shock, a life-threatening condition where your body's response to infection causes organ damage. Researchers are testing a device called Parasym that delivers Low Level Transcutaneous Vagus Nerve Stimulation. This involves gently stimulating a nerve in your ear to help your body regulate inflammation and balance your nervous system. The study aims to see if this stimulation can reduce inflammation, specifically by measuring changes in a substance called Tumor Necrosis Factor Alpha (an inflammatory cytokine). You may be able to join if you are 18 or older and have septic shock. The study is currently unclear on its recruitment status and plans to enroll 34 participants.
- Study design
- This interventional study plans to enroll 34 participants with septic shock to test a device for vagus nerve stimulation.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Researchers will measure changes in inflammation at 4 hours and 24 hours after stimulation.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Houssein Youness, MD · PRINCIPAL_INVESTIGATOR · University of Oklahoma
- Zain Ul Abideen Asad, MD · PRINCIPAL_INVESTIGATOR · University of Oklahoma
Who to contact
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Do you actually qualify for this trial?
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Exclusion
What this trial measures
- Change in Inflammatory Cytokine Tumor Necrosis Factor AlphaBaseline to 4 hours and baseline to 24 hours post stimulation
Serum inflammatory cytokine