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Clinical Outcomes for Deep Brain Stimulation in Movement Disorders

This study is looking at the real-world results of Deep Brain Stimulation (DBS) for people with Parkinson's Disease, Essential Tremor, or Dystonia. DBS is a treatment that uses high-frequency electrical stimulation to help control movement disorders. You might be able to join if you have Parkinson's that responds to levodopa, or if your Essential Tremor or Dystonia hasn't improved with other treatments. The study aims to understand how well DBS works over time, including its benefits, risks, and any problems. Researchers will measure changes in your symptoms using a tool called UPDRS one year after your DBS surgery to see how successful the treatment has been. This is an observational study, meaning researchers will collect information from people already receiving DBS.

Study design
This is an observational study that plans to include 1000 participants. It is not a randomized trial.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants' symptoms will be measured one year after Deep Brain Stimulation surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT03992625

Clinical Outcomes for Deep Brain Stimulation

Recruiting
Not specifiedAll AgesObservational
Washington University School of Medicine
~1,000 participants
Updated 2019-06-20 on ClinicalTrials.gov
What's tested:Deep Brain Stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
UPDRS
Measured over Change in UPDRS at 1 year after DBS (from preoperative baseline).

Conditions

Parkinson Disease
Essential Tremor
Dystonia

Explore related trials

DystoniaEssential TremorParkinson Disease

Where it's being run

1 sites across 1 states
Missouri1

Study leadership

  • Mwiza Ushe, M.D. · PRINCIPAL_INVESTIGATOR · Washington University School of Medicine

Who to contact

Mwiza Ushe, M.D.
[email protected]
3143625262
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Levodopa responsive Parkinson disease OR
Medically refractory Essential Tremor OR
Medically refractory Dystonia

Exclusion

Dementia (Mattis Dementia Rating Scale \<130)
Structural abnormalities precluding intracranial surgery

What this trial measures

  • UPDRSChange in UPDRS at 1 year after DBS (from preoperative baseline).

    United Parkinson's Disease Rating Scale (global assessment of motor, non-motor, and quality of life associated with symptoms of Parkinson disease). Total scores range from 0-199. Particular emphasis is paid to subsection 3 (motor), where scores range from 0-56.