Observational Study on Neighborhood Stress and Heart Health in Women

This observational study is looking at how where you live might affect your heart health. Researchers want to understand if stress from your neighborhood environment, like poverty or crime, can impact your risk for heart disease. They are also looking at how women use their neighborhoods for exercise. This study will measure stress-related brain activity in healthy women between 19 and 45 years old. Participants will be healthy White or Black women who live in Washington, D.C. The main goal is to see if living in certain neighborhoods is linked to higher levels of stress-related brain activity. The study is currently unclear on its recruitment status and aims to enroll 250 women.

Study design
This is an observational study, not testing a specific treatment. It plans to enroll 250 healthy women.
What's involved
Participants may stay at the NIH Clinical Center overnight for a 2-day visit. You will use accelerometers, GPS, and a smartphone survey.
Compensation
Not stated in the trial record.
Follow-up
Stress-related neural activity will be measured at 1 month.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04014348

Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

Recruiting
Not specifiedAges 19–45Observational
National Heart, Lung, and Blood Institute (NHLBI)
~250 participants
Updated 2026-08-28 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Stress-related neural activity
Measured over 1 month
Cardiovascular (CV) Risk

NCT04014348

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • National Institutes of Health Clinical Center

    Bethesda, Marylandstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Tiffany M Powell-Wiley, M.D. · PRINCIPAL_INVESTIGATOR · National Heart, Lung, and Blood Institute (NHLBI)

Opens a ready-to-send draft in your own email app — review before sending.

  • Stress-related neural activity1 month

    Stress-related neural activity will be estimated by neuroimaging (18-FDG PET/CT amygdala activity)