Understanding Chronic Lymphocytic Leukemia

This study aims to learn more about chronic lymphocytic leukemia (CLL) by collecting tissue samples and medical information from people with the condition. Researchers hope to understand the causes and biology of CLL better, which could lead to more effective treatments in the future. You may be able to join if you are an adult (18 years or older) with monoclonal B-cell lymphocytosis, any low-grade lymphoproliferative disorder, or chronic lymphocytic leukemia, whether you are a new or existing patient at Dana Farber Cancer Institute or elsewhere. The study will look for new genetic markers that predict how CLL might progress over 20 years. The current status of this study is unclear.

Study design
This is an observational study, meaning researchers will collect information without giving any specific interventions. It plans to enroll up to 2750 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, looking for genomic prognostic markers, will be measured at 20 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT04028531

Understanding Chronic Lymphocytic Leukemia

Recruiting
Not specifiedAges 18+Observational
Dana-Farber Cancer Institute
~2,750 participants
Updated 2026-04-24 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Incidence of novel genomic prognostic markers in Chronic Lymphocytic Leukemia
Measured over 20 years
Chronic Lymphocytic Leukemia

NCT04028531

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Dana Farber Cancer Institute

    Boston, Massachusettsstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Jennifer Brown, MD,PhD · PRINCIPAL_INVESTIGATOR · Dana-Farber Cancer Institute

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Eligibility criteria

Inclusion

New and existing patients seen for treatment of monoclonal B-cell lymphocytosis
Any low grade lymphoproliferative disorder
Chronic Lymphocytic Leukemia in the Dana Farber Cancer Institute Hematologic Oncology Clinic or elsewhere
  • Incidence of novel genomic prognostic markers in Chronic Lymphocytic Leukemia20 years

    Exploratory science to better understand Chronic Lymphocytic Leukemia