Continuous vs. Intermittent Ketorolac for Pain in Children After Heart Surgery
This study is looking at how to best manage pain in children aged 3 months to 4 years 11 months who have had heart surgery for congenital heart disease (a heart problem present at birth). Researchers want to see if giving ketorolac (a pain medication) continuously through an IV works better than giving it in occasional doses. The main goal is to find out if continuous ketorolac can reduce the amount of fentanyl (a strong pain medicine) children need in the first 96 hours after surgery. The study is currently unclear on its recruitment status, but plans to enroll 166 participants.
- Study design
- This is a prospective, randomized, double-blind, placebo-controlled study planning to enroll 166 participants.
- What's involved
- Participants will receive either continuous ketorolac or continuous placebo for 48 hours, starting within 12-24 hours after surgery.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured within 72 hours of cardiac surgery, focusing on fentanyl dose received within the first 96 hours post-operatively.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
At a glance
Conditions
NCT04040452
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Phoenix Children's Hospital
Phoenix, Arizonastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Kevin Engelhardt, MD · PRINCIPAL_INVESTIGATOR · Heart Center
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- 1. Total fentanyl dose equivalents received within the first 96 hours post-operativelyWithin 72 hours of cardiac surgery
The total opioid receipt (converted to fentanyl equivalents) administered to patients enrolled in the study within the first 96 hours after cardiac surgery.