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NCT04043442

rTMS Target Identification for Functional Disability in AUD+mTBI

Enrolling by Invitation
PHASE2Ages 22–65InterventionalTreatment
VA Office of Research and Development
~100 participants
Updated 2026-04-08 on ClinicalTrials.gov
What's tested:Magventure MagProX100 with MagOption stimulator and Magpro Cool Coil B65 A/P

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
World Health Organization Disability Assessment Schedule 2.0 (WHODAS) Change
Measured over baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 6 months

Conditions

Alcohol Use Disorder
Mild Traumatic Brain Injury

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Where it's being run

1 sites across 1 states
Illinois1

Study leadership

  • Amy A Herrold, PhD BA · PRINCIPAL_INVESTIGATOR · Edward Hines Jr. VA Hospital, Hines, IL

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Can read and speak English
Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) criteria for AUD
Symptom Attribution and Classification (SACA) criteria (Pape, Herrold et al 2016, JHTR) for mTBI (without requirement of clinical neuropsychological impairment)

Exclusion

History of moderate to severe TBI
Neurodegenerative disease (e.g., Alzheimer's disease, Parkinson's disease, multiple sclerosis)
History of or current psychotic spectrum disorders (i.e., schizophrenia, schizoaffective and bipolar disorders)
Intellectual disability (WTAR predicted full-scale IQ score \< 70)42
Are pregnant or nursing
Use of benzodiazepines, opiates, cocaine, or amphetamines in the past 30 days
Meet DSM-5 criteria for moderate to severe cannabis use disorder
Contraindications to MRI (e.g., claustrophobia, ferromagnetic metal in eyes or face, congestive heart failure, implanted cardiac pacemaker or defibrillator, cochlear implant, nerve stimulator)
Meet SACA criteria for 'Questionable Validity' of performance effort and symptom reporting

What this trial measures

  • World Health Organization Disability Assessment Schedule 2.0 (WHODAS) Changebaseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 6 months

    36-item self report measure of global functional disability. We will use the complex scoring method which creates a summary score into a metric ranging from 0 to 100 (where 0 = no disability; 100 = full disability).