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NCT04074356

Non-invasive Markers of Esophageal Function in Adults

Enrolling by Invitation
NAAges 18+InterventionalDiagnostic
Vanderbilt University Medical Center
~90 participants
Updated 2025-09-05 on ClinicalTrials.gov
What's tested:Clinical measure questionnairesEESGMESGHigh resolution manometry (HRM)

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Presence of diagnostic pattern
Measured over 3 months

Conditions

Dysphagia

Explore related trials

Dysphagia

Where it's being run

1 sites across 1 states
Tennessee1

Study leadership

  • Dhyanesh Patel, MD · PRINCIPAL_INVESTIGATOR · Vanderbilt University Medical Center

Who to contact

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adults ≥ 18 years of age who are undergoing HRM for routine standard of care evaluation for esophageal motility.
Normal control participants (ages ≥ 18 years) who have no known gastrointestinal complications.

Exclusion

Those with claustrophobia who cannot lie still under the SQUID for the length of time required
Due to interference with signal acquisition, subjects with contraindication to undergoing an MRI scan as noted in the MRI Safety checklist by Vanderbilt University Medical Center (such as with heart pacemakers, metal implants, or metal chips or clips) will not undergo SQUID, but can still be eligible to do cutaneous EESG.
Morbid obesity (these patients are potentially unable to lie under the current generation of SQUID devices)
Patients with a history of cardiac arrhythmias or taking anticoagulants will be excluded

What this trial measures

  • Presence of diagnostic pattern3 months

    EESG and MESG wave patterns will be used to see if there is a diagnostic pattern that helps identify normal function vs. the motility disorders (achalasia or hypercontractile/spastic disorders)